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Metro · Density Score

St. Louis, MO-IL

Metro area in Missouri and Illinois

54 Combined score #31 of 109 metros
Economic
59 #32 of 109
Innovation (Startup & VC)
50 #31 of 109

St. Louis ranks #31 overall, #31 in Startup & VC and #32 in Economy among 109 U.S. metros.

Highlights

  • #32 of 109: Tech share of jobs: 3.3%
  • #33 of 109: 0.15 Series B+ rounds per year per 100k people
  • #33 of 102: 0.25 startup exits per year per 100k people

The inputs

Ranks are among the metros with data for each input; higher is better.

Venture capital per year, per 100k people
$8.9M #48 of 109
Early-stage rounds per year, per 100k people
1.1 #49 of 109
Series B+ rounds per year, per 100k people
0.15 #33 of 109
Startup exits per year, per 100k people
0.25 #33 of 102
GDP per person
$84K #48 of 109
Patents per 100k people
28 #52 of 103
STEM degrees per 100k people
183 #48 of 109
Tech share of jobs
3.3% #32 of 109
Net migration of 25–44 year olds, per 100k people
-119 #72 of 109

Top companies

The largest companies headquartered in this metro, by latest annual revenue.

  1. Centene Corporation CNC · Healthcare · Clayton $195B
  2. Bunge Global SA BG · Consumer Staples · Chesterfield $70.3B
  3. Enterprise Mobility Private · Services · St. Louis $38.0B
  4. Reinsurance Group of America, Inc. RGA · Financials · Chesterfield $23.7B
  5. World Wide Technology Private · IT Software & Services · Maryland Heights $20.0B

Roots Density Data, All Companies (public: SEC filings; private: Forbes Top Private Companies 2025). Ranked by latest annual revenue.

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